Panbio登革熱抗原檢測試劑

廣州健侖生物科技有限公司

本公司為大家供應各種進口品牌登革熱檢測試劑盒，包括澳洲Panbio、美國NovaBios、美國CORTEZ等美國CDC品牌。主要包括膠體金、酶免、PCR等方法學。歡迎咨詢

Panbio登革熱抗原檢測試劑

非洲工作用登革熱試紙

熱帶國家旅游用登革熱檢測試紙

登革熱IgM抗體、登革熱IgG抗體、登革熱NS1抗原、登革熱早期檢測試劑盒

登革熱核酸檢測試劑盒

Panbio公司簡介:
1、1988年成立，2001年在澳大利亞證券交易所上市。
2、Panbio系關于蟲媒感染性疾病及熱帶感染性疾病的專業(yè)供貨商。
3、產品面向蟲媒感染性疾病的檢測，在國內疾控系統(tǒng)具有*的認知和認可度。
4、2010年銷售800萬檢測試劑，為30多種疾病提供診斷。

Panbio登革熱介紹：

1、登革熱快速檢測試劑(Dengue Duo Cassette R-DEN03D)
用于定性的快速檢測人群血清、血漿或全血中登革病毒的IgM及IgG抗體。可在15分鐘內檢測結果。

2、登革IgM捕捉ELISA(Dengue IgM Capture ELISA E-DEN01M)
用于定性的檢測人群血清中登革病毒的IgM抗體，用于臨床實驗室對具有持續(xù)發(fā)燒的登革熱癥狀的病人的輔助診斷。

3、登革IgG捕捉ELISA(Dengo IgG Capture ELISA E-DEN02G)
用于定性檢測血清中登革病毒(血清型1、2、3及4型)的IgG抗體。用于臨床實驗室對繼發(fā)登革熱感染的輔助診斷。

4、登革早期ELISA(Dengue Early ELISA E-DEN01P)
用于定性檢測血清中登革病毒的NS1抗原(血清型1、2、3及4型)。用于臨床實驗室對有持續(xù)發(fā)燒的登革熱癥狀病人的輔助性診斷。

5、登革IgG間接ELISA(Dengue IgG Indirect ELISA E-DEN01G)
用于定性檢測血清中登革病毒(血清型1、2、3及4型)的IgG抗體，用于臨床實驗室對具有持續(xù)發(fā)燒的登革感染癥狀或接觸史的患者的輔助性診斷。

6、登革IgM & IgG聯(lián)檢ELISA(Dengue Duo IgM & IgG Capture ELISA E-DEN01D)
用于定性檢測血清中登革病毒的IgM和IgG抗體?？梢詤^(qū)分原發(fā)感染與繼發(fā)感染。

Dengue產品介紹

Panbio

登革熱病是由登革熱病毒引起，主要通過伊蚊叮咬傳播的急性傳染病。臨床以高熱、頭痛、黃疸、蛋白尿、相對緩脈和出血等為主要表現(xiàn)。本病在非洲和南美洲的熱帶和亞熱帶呈地方性流行，亞洲尚無本病報告。由于登革熱病的死亡率高及傳染性強，已納入世界衛(wèi)生組織規(guī)定之檢疫傳染病之一。
病因
登革熱病病毒屬蟲媒病毒B組披膜病毒科，病毒直徑22～38納米，呈球形，有包膜，含單股正鏈RNA。易被熱、常用消毒劑、Panbio登革熱、去氧膽酸鈉等滅活，但在血中能于4℃保存1個月，在50%甘油中于0℃下可存活數(shù)月，于-70℃或冷凍干燥條件下可保持活力數(shù)年。zui初分離的登革熱病毒Asibi株通過組織培養(yǎng)弱化成17D株，用以制備減毒活疫苗，預防效果良好。
臨床表現(xiàn)
潛伏期3～6天。多數(shù)受染者癥狀較輕，可僅表現(xiàn)為發(fā)熱、頭痛、輕度蛋白尿等，持續(xù)數(shù)日即恢復。重型患者只發(fā)生在約15%的病例。病程經(jīng)過可分為4期。
1.感染期
急起高熱伴有寒戰(zhàn)、劇烈頭痛及全身痛，明顯乏力、食欲不振、惡芯、嘔吐、腹瀉或便秘等。患者煩躁不安，結膜充血，面、頸潮紅。心率與發(fā)熱平行，以后轉為相對心搏徐緩。本期持續(xù)約3天，此時病毒在血中達高滴度，成為蚊蟲感染的來源。期末可有輕度黃疸、蛋白尿。
2.緩解期
發(fā)熱部分或*消退，癥狀緩解，持續(xù)數(shù)小時至24小時。
3.中毒期
發(fā)熱與癥狀復現(xiàn)，且更加重。此期毒血癥消退，出現(xiàn)肝、腎、心血管功能損害以及出血癥狀。血清膽紅素明顯升高，凝血酶原時間延長，蛋白尿、少尿與氮質血癥的程度和病情成正比。本期突出癥狀為嚴重的出血如齒齦出血、鼻出血、皮膚黏膜淤斑、胃腸道、尿道和子宮出血等。心臟常擴大，心搏徐緩，心音變弱，血壓降低。常伴有脫水、酸中毒，嚴重者出現(xiàn)譫妄、昏迷、尿閉、頑固性呃逆、大量嘔血、休克等。本期持續(xù)3～4天或2周。常在第7～10天發(fā)生死亡。
4.恢復期
體溫下降至正常。癥狀和蛋白尿逐漸消失，但乏力可持續(xù)1～2周或更久。此期仍需密切觀察心臟情況，個別病例可因心律不齊或心功能衰竭死亡。存活病例一般無后遺癥。
實驗室及其他檢查
1.一般常規(guī)和生化檢查
外周血白細胞總數(shù)正?；蛏?，但在本病早期中性粒細胞數(shù)常減少。血小板計數(shù)正?；驕p少。血清膽紅素、ALT和AST升高，死亡病例更為明顯。有黃疸的病例凝血酶原時間及部分凝血活酶時間延長。尿蛋白增多、血清尿素及肌酐升高。
2.病毒分離
采取病初3～4天內血標本接種小白鼠腦內或細胞培養(yǎng)可分離出病毒并用血清學方法進行鑒定。

Panbio

我司還提供其它進口或國產試劑盒：登革熱、瘧疾、乙腦、寨卡、黃熱病、基孔肯雅熱、克錐蟲病、違禁品濫用、肺炎球菌、軍團菌等試劑盒以及日本生研細菌分型診斷血清、德國SiFin診斷血清、丹麥SSI診斷血清等產品。

想了解更多的Panbio產品及服務請掃描下方二維碼：

【公司名稱】 廣州健侖生物科技有限公司
【市場部】    楊永漢

【】 
【騰訊  】 2042552662
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號二期2幢101-103室

references：

Dengue fever is caused by dengue virus, mainly through the mosquito bites spread of acute infectious diseases. Clinical to high fever, headache, jaundice, proteinuria, relative slow pulse and bleeding as the main performance. The disease in Africa and South America, tropical and subtropical was local epidemic, Asia, no disease reported. Due to the high mortality and contagious nature of dengue fever, it has been included in one of the quarantine infectious diseases prescribed by the World Health Organization.
Etiology
Dengue virus is a parasitic virus virus B group Phaffia virus family, the virus diameter of 22 to 38 nm, spherical, with a single strand of positive strand RNA. Easy to be hot, commonly used disinfectants, Panbio dengue fever, sodium deoxycholate and other inactivation, but in the blood can be stored at 4 ℃ for 1 month in 50% glycerol at 0 ℃ can survive for several months, at -70 ° C or freeze-drying conditions can be maintained for several years. The original isolated dengue virus Asibi strain was weighed into tissue 17D strain to prepare attenuated live vaccine, and the prevention effect was good.
Clinical manifestations
Incubation period of 3 to 6 days. Most of the infected people mild symptoms, can only show fever, headache, mild proteinuria, etc., for several days to recover. Severe patients only occur in about 15% of cases. The course of the disease can be divided into four periods.
Infection period
Acute high fever accompanied by chills, severe headache and body pain, obvious fatigue, loss of appetite, evil core, vomiting, diarrhea or constipation. Patients with irritability, conjunctival hyperemia, face, neck flushing. Heart rate and fever parallel, later to relatively slow heartbeat. This period lasts about 3 days, this time the virus in the blood of high titer, become the source of mosquito infection. At the end of the period may have mild jaundice, proteinuria.
2. Remission period
Fever partial or complete regression, symptom relief, lasted several hours to 24 hours.
3. poisoning period
Fever and symptoms recur, and more emphasis. This period of toxemia subsided, liver, kidney, cardiovascular damage and bleeding symptoms. Serum bilirubin was significantly increased, prothrombin time prolonged, proteinuria, oliguria and azotemia and the degree of disease is proportional to the disease. This period highlights the symptoms of severe bleeding such as gum bleeding, epistaxis, skin and mucous membrane eczema, gastrointestinal tract, urethra and uterine bleeding. The heart often expanded, heart beat slowly, heart sounds weak, lower blood pressure. Often accompanied by dehydration, acidosis, severe delirium, coma, urinary closure, intractable hiccups, a large number of hematemesis, shock and so on. This period lasts 3 to 4 days or 2 weeks. Often in the first 7 to 10 days of death.
4. recovery period
Body temperature dropped to normal. Symptoms and proteinuria gradually disappear, but the fatigue can last 1 to 2 weeks or longer. This period still need to closely observe the heart, individual cases may be due to arrhythmia or heart failure death. Survival cases are generally no sequelae.
Laboratory and other inspections
1. General routine and biochemical tests
Peripheral white blood cells in the normal or elevated, but in early childhood the number of neutrophils often reduced. Plaet counts are normal or reduced. Serum bilirubin, ALT and AST increased, more serious cases of death. The time of prothrombin time and partial thromboplastin prolongation in patients with jaundice. Increased urinary protein, serum urea and creatinine increased.
2. virus isolation
To take the first 3 to 4 days of the disease blood samples inoculated with the mouse brain or cell culture can be isolated from the virus and serological methods for identification.