其它名稱:免疫球蛋白IgG4蛋白,IgG4 protein,IgG4抗原
貨號:G7043
種類:抗原
應用:Standard
特異性:Human IgG4
來源:重組蛋白
存貯:-20℃
免疫球蛋白IgG,由B淋巴細胞激活的漿細胞分泌產生。是人血清中豐富的蛋白質之一。IgG又分為四種亞型(IgG1,IgG2,IgG3,IgG4),最主要的是IgG1,而IgG4占總IgG的5%左右。
產品說明
IgG1 immunoglobulin is most prevalent (>50%) and the IgG4 variety constitutes less than 5%. IgG4 has disulfide bonds linking the heavy chains unsteadily, allowing their separation and forming 2 antigen-binding sites, so that the bispecific antibody is asymmetric with an unclear in vivo role. IgG4 interacts with the Fc portion of IgG1–3 and not through the Fab-Fc, as occurs with other immunoglobulins, and has rheumatoid factor activity. Therefore, IgG4 has little or no cross-reactivity between antigens and rarely forms immune complexes having no complement activation capacity
This product is for research use only. It is not intended for diagnostic or therapeutic use.
IgG4抗原注意事項:
1.本品為蛋白質制劑,未添加任何防腐劑和保護劑,在2-8℃可短期保存
2.本品作為診斷試劑原輔材料,不得直接用于診斷或治療。