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FITC標記的腺苷脫氨酶抗體

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  • 公司名稱上海泛柯實業有限公司
  • 品       牌
  • 型       號
  • 所  在  地上海
  • 廠商性質經銷商
  • 更新時間2015/5/8 11:26:05
  • 訪問次數527
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FITC標記的腺苷脫氨酶抗體產品介紹:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FITC標記的腺苷脫氨酶抗體 產品信息
英文名稱Anti-Adenosine deaminase/FITC
中文名稱FITC標記的腺苷脫氨酶抗體
別    名ada; ADA_HUMAN; Adenosine aminohydrolase; Adenosine deaminase.
說 明 書100ul  
研究領域腫瘤  細胞生物  信號轉導  表觀遺傳學  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Human, Mouse, Rat, Pig, Cow, Horse, 
產品應用IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量40kDa
細胞定位細胞膜 
性    狀Lyophilized or Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Adenosine deaminase
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹background:
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion.

Function:
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion.

Subunit:
Interacts with DPP4 (extracellular domain).

Subcellular Location:
Cell membrane; Peripheral membrane protein; Extracellular side. Cell junction. Cytoplasmic vesicle lumen. Cytoplasm.

Tissue Specificity:
Found in all tissues, occurs in large amounts in T-lymphocytes and, at the time of weaning, in gastrointestinal tissues.
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