磷酸化水通道蛋白2抗體*
『別名』Aquaporin 2 (phospho S256); Aquaporin 2 (phospho Ser256); p-Aquaporin 2 (phospho S256); p-Aquaporin 2 (S256); ADH water channel; AQP 2; AQP CD; AQP2; AQPCD; Aquaporin 2 collecting duct; Aquaporin CD; Aquaporin2; Aquaporine 2; Collecting duct water channel protein; MGC34501; Water channel protein for renal collecting duct; WCH CD; WCHCD; AQP2_HUMAN.
『濃度』1mg/1ml
『規(guī)格』0.1ml/100μg
『抗體來源』Rabbit
『克隆類型』polyclonal
『交叉反應(yīng)』Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Monkey
『產(chǎn)品類型』一抗 磷酸化抗體
『研究領(lǐng)域』腫瘤 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 通道蛋白 細(xì)胞粘附分子
『蛋白分子量』predicted molecular weight: 29kDa
『性狀』Lyophilized or Liquid
『免疫原』KLH conjugated synthesised phosphopeptide derived from human AQP2 around the phosphorylation site of Ser256
『亞型』IgG
『純化方法』affinity purified by Protein A
『儲存液』Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
『產(chǎn)品應(yīng)用』WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
『保存條件』Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
『產(chǎn)品介紹』Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by磷酸化水通道蛋白2抗體* vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation, and the secretion and reabsorption of cerebrospinal fluid and aqueous humor.
Function : Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
Subcellular Location : Apical cell membrane. Cytoplasmic vesicle membrane. Shuttles from vesicles to the apical membrane.
Tissue Specificity : Expressed in renal collecting tubules.
Post-translational modifications : Ser-256 phosphorylation is necessary and sufficient for expression at the apical membrane. Endocytosis is not phosphorylation-dependent.
DISEASE : Defects in AQP2 are the cause of diabetes insipidus nephrogenic autosomal (ANDI) [MIM:125800]; also known as diabetes insipidus nephrogenic type 2. ANDI is caused by the inability of the renal collecting ducts to absorb water in response to arginine vasopressin. It is characterized by excessive water drinking (polydypsia), excessive urine excretion (polyuria), persistent hypotonic urine, and hypokalemia. Inheritance can be autosomal dominant or recessive.
Similarity : Belongs to the MIP/aquaporin (TC 1.A.8) family.
Database links : UniProtKB/Swiss-Prot: P41181.1
E-(Hu)（03）-00683 人胚胎性硫糖蛋白抗原(FSA)elisa試劑盒 ，英文名： fetal sulfoslycoprotein antigen,FSA ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00684 人本周蛋白(BJP) elisa試劑盒 ，英文名： Bence-Jones protein,BJP ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00685 人癌胚鐵蛋白(CEF) elisa試劑盒 ，英文名： Carcinoembryonic Ferritin,CEF ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00686 人鱗狀細(xì)胞癌相關(guān)抗原(SCCAg)elisa試劑盒 ，英文名： squamous cell carcinoma related antigen,SCCAg ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00687 人腫瘤特異性抗原(TSA) elisa試劑盒 ，英文名： tumor specific antigen,TSA ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00688 人黑色素瘤轉(zhuǎn)移表面黏附分子(MMSAM)elisa試劑盒 ，英文名： melanoma metastasis surface adhesion molecule,MMSAM ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00689 人乳腺癌易感蛋白2(BRCA-2)elisa試劑盒 ，英文名： breast cancer susceptibility protein 2,BRCA-2 ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00690 人凋亡信號調(diào)節(jié)激酶I(ASK-1)elisa試劑盒 ，英文名： apoptosis signal regulating kinase 1,ASK-1 ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00691 人Bcl-2相關(guān)X蛋白(BAX)elisa試劑盒 ，英文名： Bcl-2 associated X protein, Bax ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00692 人H-ras elisa試劑盒 ，英文名： H-ras ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00693 人c-sis elisa試劑盒 ，英文名： c-sis ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00694 人c-jun elisa試劑盒 ，英文名： c-jun ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00695 人c-fos elisa試劑盒 ，英文名： c-fos ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00696 人c-myc癌基因產(chǎn)物(c-myc)elisa試劑盒 ，英文名： c-myc Oncogene product,c-myc ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00697 人Smad1 elisa試劑盒 ，英文名： Mothers against decapentaplegic homolog 1,Smad1 ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00698 人Smad7 elisa試劑盒 ，磷酸化水通道蛋白2抗體* 英文名： Mothers against decapentaplegic homolog 7,Smad7 ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00699 人腫瘤相關(guān)抗原(TAA)elisa試劑盒 ，英文名： tumor-associated antigen,TAA ELISA Kit ，規(guī)格： 96T/48T
會員1.png)