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上海瑞齊實業科技有限公司


當前位置:上海瑞齊實業科技有限公司>公司動態>Anti-ATF3抗體*,有好禮

經營模式:代理商

商鋪產品:9957條

所在地區:上海上海市

聯系人:周經理 (經理)

公司動態

Anti-ATF3抗體*,有好禮

閱讀:486發布時間:2013-12-20

 Anti-ATF3

Catalog Number : Rs-0519R

Quantity size :   0.1ml  (dilute with pH 7.4    0.01 M PBS or antibody diluent )

Background:

Theactivating transcription factor 3 belong to contain the turn of sour zipperstructure of bright ammonia to record the factor ATF/ CREB household member,present the low density Stable appearance expression in big and part of normalcell.The ATF3 not only in should arouse respond is adjusts to control thefactor decisively, but also participated the machine body Stable appearancemaintenance, wound extensively to match more, the cell sticks to attach,physiologies such as the tumor formation, Apoptosis and the signal conductionetc. and pathologic process.The ATF3 and the cell existences have relation withApoptosis.

Function: This protein binds the cAMP response element (CRE) (consensus:5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellularpromoters. Represses transcription from promoters with ATF sites. It mayrepress transcription by stabilizing the binding of inhibitory cofactors at thepromoter. Isoform 2 activates transcription presumably by sequesteringinhibitory cofactors away from the promoters.

Similarity: Belongs to the bZIP family. ATF subfamily.

Contains1 bZIP domain

.pecificity:    

-     Anti-ATF3 is a   Rabbit  polyclonal antibody unconjugated                 

specific for ATF3 of  Human, Mouse, Rat, Chicken, Dog, Cow,

use for western blotting,elisa,immunoprecipitation andimmunohistochemistry

    Protein G affinity chromatography purification,purity :>95%

    Isotype: IgG

Application :  

     WB=1:100-500 ELISA=1:500-1000 IP=1:20-100IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user..

Storage:  Store at-20 for one year.Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least onemonth and for greater  than a year whenkept at -20. Whenreconstituted in sterile pH 7.4 0.01M PBS or diluent  of antibody, the antibody is stable for atleast six weeks at 2-4

 

Important Note:This product as supplied is intended for research use only, not for use in  human, therapeutic or diagnostic applications.


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