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Anti-Phospho-BRCA1(Ser1524),磷酸化乳腺癌易感基因1抗體科研

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更新時間:2018-04-30 04:04:57瀏覽次數:179次

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“Anti-Phospho-BRCA1(Ser1524),磷酸化乳腺癌易感基因1抗體科研"我公司擁有*的細胞服務技術,*的儀器設備和專業的ELISA檢測試劑盒、生物索標記、熒光索標記、酶標記等,廣泛用于多種分析研究與技術測定。咨詢,我們將竭誠為你服務!

詳細介紹

Anti-Phospho-BRCA1(Ser1524),磷酸化乳腺癌易感基因1抗體科研產品介紹:

This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability and acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as BASC for BRCA1-associated genome surveillance complex. This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complex. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximay 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants have been described for this gene but only some have had their full-length natures identified. Transcript Variant: This variant (BRCA1a') uses different splice site in the 5' UTR when compared to variant BRCA1a. It encodes the full-length BRCA1 protein (isoform 1) which is also known as p220. Variants BRCA1a and BRCA1b also encode the full-length BRCA1 protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.


與“Anti-Phospho-BRCA1(Ser1524),磷酸化乳腺癌易感基因1抗體科研"有關的產品:

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嗜酸粒細胞趨化蛋白3抗體 Anti-CCL26/Eotaxin 3
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Anti-Phospho-BRCA1(Ser1524),磷酸化乳腺癌易感基因1抗體科研產品詳情:
產品編號:HRK-3014R
產品規格: 0.1ml/0.2ml
產品別名:BRCA1(Phospho-Ser1524); BRCA1 (phospho S1524); p-BRCA1 (phospho S1524); BRCA 1; BRCA1; BRCA1/BRCA2 containing complex subunit 1; BRCA1/BRCA2-containing complex, subunit 1; BRCA1_HUMAN; BRCAI; BRAC 1; BRCA 1; BRCC 1; BRCC1; Breast Cancer 1; Breast Cancer 1 Early Onset; Breast cancer type 1 susceptibility protein; Breast and ovarian cancer susceptibility protein 1; Breast Ovarian Cancer Susceptibility; IRIS; Papillary Serous Carcinoma Of The Peritoneum; PSCP; RING finger protein 53; BROVCA1; IRIS; PNCA4; PPP1R53; Protein phosphatase 1 regulatory subunit 53; RNF53; BAP1
產品價格:詢價(電詢或客服)
產品用途:科研實驗
貯 存:   貯存于-20℃.

與“Anti-Phospho-BRCA1(Ser1524),磷酸化乳腺癌易感基因1抗體科研"有關的其他產品:

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Anti-CEA (Carcinoembryonic Antigen )  人癌胚抗原抗體
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