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華瑞科研網-ELISA試劑盒
“Anti-CD272抗體,B和T淋巴細胞衰減蛋白抗體科研"我公司擁有*的細胞服務技術,*的儀器設備和專業的ELISA檢測試劑盒、生物索標記、熒光索標記、酶標記等,廣泛用于多種分析研究與技術測定。咨詢,我們將竭誠為你服務!
Anti-CD272抗體,B和T淋巴細胞衰減蛋白抗體科研產品介紹:
B and T lymphocyte attenuator (BTLA), an immunoglobulin domain-containing glycoprotein with two immunoreceptor tyrosine-based inhibitory motifs. BTLA is not expressed by naive T cells, but it is induced during activation and remains expressed on T helper type 1 (T(H)1) but not T(H)2 cells. Crosslinking BTLA with antigen receptors induces its tyrosine phosphorylation and association with the Src homology domain 2 (SH2)-containing protein tyrosine phosphatases SHP-1 and SHP-2, and attenuates production of interleukin 2 (IL-2). BTLA-deficient T cells show increased proliferation, and BTLA-deficient mice have increased specific antibody responses and enhanced sensitivity to experimental autoimmune encephalomyelitis. B7x, a peripheral homolog of B7, is a ligand of BTLA. Thus, BTLA is a third inhibitory receptor on T lymphocytes with similarities to cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and programmed death 1 (PD-1).
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產品詳情:
產品編號:HRK-0624R
產品規格: 0.1ml/0.2ml
產品別名:B and T lymphocyte associated protein; B and T lymphocyte attenuator; B and T lymphocyte associated; BTLA; BTLA1; CD272 antigen; FLJ16065; MGC129743; BTLA_HUMAN; B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; CD272
產品價格:詢價(電詢或客服)
產品用途:科研實驗
貯 存: 貯存于-20℃.
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