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華瑞科研網(wǎng)-ELISA試劑盒
華瑞科研網(wǎng)-ELISA試劑盒
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更新時間：2018-04-14 02:35:17瀏覽次數(shù)：405次
聯(lián)系我時，請告知來自 智慧城市網(wǎng)“Anti-CDT2抗體,維甲酸調(diào)節(jié)核基質(zhì)相關(guān)蛋白抗體科研“我公司擁有*的細胞服務(wù)技術(shù)，*的儀器設(shè)備和專業(yè)的ELISA檢測試劑盒、生物索標記、熒光索標記、酶標記等，廣泛用于多種分析研究與技術(shù)測定。咨詢，我們將竭誠為你服務(wù)！
Anti-CDT2抗體,維甲酸調(diào)節(jié)核基質(zhì)相關(guān)蛋白抗體科研產(chǎn)品介紹：
Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21(CIP1). CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication. CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing. Most substrates require their interaction with PCNA for their polyubiquitination: substrates interact with PCNA via their PIP-box, and those containing the 'K+4' motif in the PIP box, recruit the DCX(DTL) complex, leading to their degradation. In undamaged proliferating cells, the DCX(DTL) complex also promotes the 'Lys-164' monoubiquitination of PCNA, thereby being involved in PCNA-dependent translesion DNA synthesis.
Tissue specificity: Expressed in placenta and testis, very low expression seen in skeletal muscle. Detected in all hematopoietic tissues examined, with highest expression in thymus and bone marrow. A low level detected in the spleen and lymph node, and barely detectable level in the peripheral leukocytes. RA treatment down-regulated the expression in NT2 cell.
與“Anti-CDT2抗體,維甲酸調(diào)節(jié)核基質(zhì)相關(guān)蛋白抗體科研"有關(guān)的產(chǎn)品：
Anti-ILT2/CD85j(Immunoglobulin-like transcript 2) 細胞表面免疫球蛋白樣轉(zhuǎn)錄因子2抗體
Anti-IRS P53 (Insulin receptor substrate P53) 胰島素受體底物p53蛋白抗體
Anti-IRS-1 胰島素受體底物-1抗體
Anti-IRS-2 胰島素受體底物-2抗體
Anti-IRS-3 胰島素受體底物-3抗體
Anti-IRS-4 胰島素受體底物-4抗體
Anti-ISR（Insulin Receptor）（hu, cattle, mo, rat, horse, sheep, Rb, dog, chi） 胰島素受體抗體
Anti-ISR-α （Insulin Receptor-α） 胰島素受體-α抗體
Anti-ISR-β （Insulin Receptor-β） 胰島素受體-β抗體
Anti-Integrin α4/CD49d(Integrin alpha 4) 整合素α4抗體
產(chǎn)品詳情：
產(chǎn)品編號：HRK-7935R
產(chǎn)品規(guī)格: 0.1ml/0.2ml
產(chǎn)品別名：Lethal(2) denticleless protein homolog; CDW1; CDW1; DCAF2; DDB1 and CUL4 associated factor 2; Ddb1- and Cul4-associated factor 2; Denticleless homolog; Denticleless homolog (Drosophila); Denticleless protein homolog; Dtl; DTL_HUMAN; L2DTL; Lethal(2) denticleless protein homolog; RA regulated nuclear matrix associated protein; RAMP; Retinoic acid regulated nuclear matrix associated protein; Retinoic acid-regulated nuclear matrix-associated protein
產(chǎn)品價格：詢價(電詢或客服)
產(chǎn)品用途：科研實驗
貯 存： 貯存于-20℃.
與“"有關(guān)的其他產(chǎn)品：
*受體δ2/GluR-δ2抗體 Anti-GRID2IP
活性氧簇ROS抗體 Anti-ROS/c ros
共濟失調(diào)性眼球運動功能喪失相關(guān)蛋白AOA1抗體 Anti-AOA1/Aprataxin
酸性核糖體磷蛋白大亞基P0抗體 Anti-RPLP0
Meteorin神經(jīng)膠質(zhì)細胞分化調(diào)節(jié)蛋白抗體 Anti-METRN
Rho相關(guān)蛋白激酶2抗體 Anti-ROCK2
低密度脂蛋白受體相關(guān)蛋白9抗體 Anti-SorLA/LRP9
Rho相關(guān)蛋白激酶1抗體 Anti-ROCK1
環(huán)指蛋白148抗體 Anti-RNF148
鈣磷蛋白2抗體 Anti-Calcyphosine 2/CAPS2
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