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華瑞科研網-ELISA試劑盒
“Anti-CPLX2抗體,Complexin II/復合素2抗體科研“我公司擁有*的細胞服務技術,*的儀器設備和專業的ELISA檢測試劑盒、生物索標記、熒光索標記、酶標記等,廣泛用于多種分析研究與技術測定。咨詢,我們將竭誠為你服務!
Anti-CPLX2抗體,Complexin II/復合素2抗體科研產品介紹:
Complexin 1 and Complexin 2, also designated Synaphin 1 and Synaphin 2, contain an a-helical middle domain of approximay 58 amino acids. Complexin 1 and Complexin 2 are expressed in presynaptic terminals of inhibitory and excitatory hippocampal neurons, respectively, and in cytoplasmic pools during early stages of development. Complexins promote SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) precomplex formation by binding to synaxin with its a-helical domain. Complexins are important regulators of transmitter release at a late step in calcium dependent neurotransmitter release or immediay after the calcium-triggering step of fast synchronous transmitter release and preceding vesicle fusion. Neurons lacking complexins show reduced transmitter release efficiency due to decreased calcium sensitivity of the synaptic secretion process. Complexin 2 may play a role in LTP (long term potentiation) following tetanic stimulation. A progressive loss of Complexin 2 occurs in the brains of mice carrying the Huntington disease mutation, an autosomal dominant neurodegenerative disorder. Changes in the neurotransmitter release might contribute to the motor, emotional and cognitive dysfunctions seen in these mice.
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產品詳情:
產品編號:HRK-11342R
產品規格: 0.1ml/0.2ml
產品別名:Complexin 2; Complexin II; Complexin-2; Complexin2; ComplexinII; CPLX 2; Cplx2; CPLX2_HUMAN; CPX 2; CPX II; CPXII; Hfb1; Synaphin 1; Synaphin-1; Synaphin1; 921 L
產品價格:詢價(電詢或客服)
產品用途:科研實驗
貯 存: 貯存于-20℃.
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