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華瑞科研網(wǎng)-ELISA試劑盒
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華瑞科研網(wǎng)-ELISA試劑盒
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更新時(shí)間：2015-04-09 09:39:34瀏覽次數(shù)：241次
聯(lián)系我時(shí)，請(qǐng)告知來(lái)自 智慧城市網(wǎng)“Anti-Cytohesin 2抗體,胞粘蛋白2抗體科研“我公司擁有*的細(xì)胞服務(wù)技術(shù)，*的儀器設(shè)備和專業(yè)的ELISA檢測(cè)試劑盒、生物索標(biāo)記、熒光索標(biāo)記、酶標(biāo)記等，廣泛用于多種分析研究與技術(shù)測(cè)定。咨詢，我們將竭誠(chéng)為你服務(wù)！
Anti-Cytohesin 2抗體,胞粘蛋白2抗體科研產(chǎn)品介紹：
The ADP-ribosylation factor (Arf) family comprises a group of structurally and functionally conserved 21 kDa proteins, which are members of the Ras superfamily of regulatory GTP-binding proteins. Arf is involved in intracellular protein traffic to and within the Golgi complex. Arf has a number of disparate activities including maintenance of organelle integrity, assembly of coat proteins, as a co-factor for cholera toxin and as an activator of phospholipase D. Like other small GTPases, Arf is found to be active when bound to GTP and inactive when bound to GDP. Arf’s activation is dependent upon guanine nucleotide exchange factors (GEFs) which increase the rate of exchange of bound GDP with GTP. All GEFs have a highly conserved Sec7 domain. GEF activity lies in the Sec7 domain and this activity has been shown to be inhibited by the fungal metabolite brefeldin-A (BFA). A small group of GEFs which are insensitive to brefeldin-A (BFA) include cytohesin-1 (B2-1), cytohesin-2 (ARNO), cytohesin-3 (ARNO3), and cytohesin-4. All cytohesins function in the cell periphery and contain a pleckstrin homology (PH) domain. The PH domain has been shown to interact with phosphatidylinositol 3,4,5-triphosphate and is believed to promote membrane targeting of the cytohesins. Recruitment of the cytohesins to the membranes can occur in response to tyrosine kinase receptor activation. This response appears to require the activation of phosphatidylinositol 3-kinase (PI 3-kinase).
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產(chǎn)品詳情：
產(chǎn)品編號(hào)：HRK-12922R
產(chǎn)品規(guī)格: 0.1ml/0.2ml
產(chǎn)品別名：ARF exchange factor; ARF nucleotide binding site opener; Arno; ARNO protein; CLM2; CTS18; CTS18.1; Cyth2; Cytohesin 2; MGC137537; MGC80440; PH, SEC7 and coiled-coil domain-containing protein 2; Pleckstrin homology Sec7 and coiled coil domains 2; Pleckstrin homology Sec7 and coiled coil domains protein 2; PSCD2; PSCD2L; PSCD2L, formerly; Sec7; SEC7 homolog B; Sec7B; SEC7L; Sec7p L; Sec7p-like; Sec7pL; CYH2_HUMAN
產(chǎn)品價(jià)格：詢價(jià)(電詢或客服)
產(chǎn)品用途：科研實(shí)驗(yàn)
貯 存： 貯存于-20℃.
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