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Anti-CHK2（Ser28）,磷酸化細(xì)胞周期檢測點激酶2抗體科研

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“Anti-CHK2（Ser28）,磷酸化細(xì)胞周期檢測點激酶2抗體科研“我公司擁有*的細(xì)胞服務(wù)技術(shù)，*的儀器設(shè)備和專業(yè)的ELISA檢測試劑盒、生物索標(biāo)記、熒光索標(biāo)記、酶標(biāo)記等，廣泛用于多種分析研究與技術(shù)測定。咨詢，我們將竭誠為你服務(wù)！

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Anti-CHK2(Ser28),磷酸化細(xì)胞周期檢測點激酶2抗體科研產(chǎn)品介紹：

In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the encoded protein is known to inhibit CDC25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1. In addition, this protein interacts with and phosphorylates BRCA1, allowing BRCA1 to restore survival after DNA damage. Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53. Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors. This nuclear protein is a member of the CDS1 subfamily of serine/threonine protein kinases. Several transcript variants encoding different isoforms have been found for this gene.

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Anti-CHK2(Ser28),磷酸化細(xì)胞周期檢測點激酶2抗體科研產(chǎn)品詳情：
產(chǎn)品編號：HRK-13907R
產(chǎn)品規(guī)格: 0.1ml/0.2ml
產(chǎn)品別名：Chk2 (phospho S28); p-Chk2 (phospho S28); bA444G7; CHK2 checkpoint homolog; CHK2_HUMAN; Serine/threonine-protein kinase Chk2; CDS 1; CDS1; Checkpoint kinase 2; Checkpoint like protein CHK2; Chek 2; Chek2; Chk 2; CHK2 checkpoint homolog (S. pombe); CHK2 checkpoint homolog; HuCds 1; HuCds1; LFS 2; LFS2; PP1425; RAD 53; RAD53; Rad53 homolog; Serine/threonine protein kinase Chk2
產(chǎn)品價格：詢價(電詢或客服)
產(chǎn)品用途：科研實驗
貯存：貯存于-20℃.

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