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閱讀：1743發布時間：2013-10-1
Anti-NF-kB抗體說明書
From:ABCAM
Catalog Number :RS-1852R
Quantity size : 0.1ml （dilute with pH 7.4 0.01 M PBS or antibody diluent ） Background: Annexin V （ANX5） is a member of a family of calcium-dependent phospholipid binding proteins. This family of annexins also includes giardin that has been shown to function as an annexin; pfam00191
This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B （NFKB） protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. SUBUNIT: Active NF-kappa-B is a heterodimer of an about 50 kDa DNA-binding subunit and the weak DNA-binding subunit p65. Two heterodimers might form a labile tetramer. Also interacts with MAP3K8. NF-kappa-B p50 subunit interacts with NCOA3 coactivator, which may coactivate NF-kappa-B dependent expression via its histone acetyltransferase activity. Interacts with DSIPI; this interaction prevents nuclear translocation and DNA-binding. Interacts with SPAG9 and UNC5CL.
Specificity : Anti- PSA/FITC a mouse polyclonal antibody
specific for PSA /FITC of Human, Rat, Pig, Rabbit
Application :
Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
商鋪：http://www.cmr6829.com/st132832/
主營產品：流式標記抗體，FITC,PE,CY3,5,7標記ELISA試劑盒、生化檢測試劑盒、金標檢測試劑盒、分子生物學試劑盒、進口國產胎牛血清、生物抗體、細胞，試劑耗材
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