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技術文章

CTLA-4抗體Anti-CTLA-4抗體

閱讀:497發布時間:2013-10-2

CTLA-4抗體Anti-CTLA-4抗體

Catalog Number :Rs-10752R

Quantity size :   0.1ml  (dilute with pH 7.4    0.01 M PBS or antibody diluent ) Background: Annexin V (ANX5) is a member of a family of calcium-dependent phospholipid binding proteins. This family of annexins also includes giardin that has been shown to function as an annexin; pfam00191
 

CTLA-4抗體Anti-CTLA-4抗體This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

 

Specificity : Anti- CTLA-4 a rabbit polyclonal antibody             

specific for CTLA-4 of Human, Mouse Rat,

  • use for western blotting,elisa,immunoprecipitation and immunohistochemistry
  • Protein G affinity chromatography purification, purity :>95%
  • Isotype:  IgG
  • mol wt:  21kDa

Application :  

  •   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  ICC=1:100-500  IF=1:100-500
  • Excitation spectrum:490-495nm
  • Emission spectrum:520-530nm
  • not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.

Storage:  CTLA-4抗體Anti-CTLA-4抗體Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The  lyophilized antibody is stable at room temperature for at least one month and for greater  than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent  of antibody, the antibody is stable for at least six weeks at 2-4 ℃

 

Important Note: This product as supplied is intended for research use only, not for use in  human, therapeutic or diagnostic applications.

 


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