描述 | 這是一株超三倍體人類細胞株。 其典型染色體數為71，發生率為34%，多倍體率為2.6%。 t(4;11)(p15;q13), i(13q), t(10p15q), del(18)(q21),和6個其他標記在大多數細胞中常見，另有兩個標記在一些細胞中可見。 在一個N14和兩個N22中可見大衛星。 N2, N5, 和 N9 有4個拷貝，而N7, N13, N18, N21 和 X為單拷貝。 Q-帶檢測法可以檢測到單個Y染色體。 |
REFERENCE | Fogh J , et al. Absence of HeLa cell contamination in 169 cell lines derived from human tumors. J. Natl. Cancer Inst. 58: 209-214, 1977. PubMed: 833871 Fogh J , et al. One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice. J. Natl. Cancer Inst. 59: 221-226, 1977. PubMed: 327080 Acta Endocrinol. Suppl. 153: 137-153, 1971. Landers JE , et al. Translational enhancement of mdm2 oncogene expression in human tumor cells containing a stabilized wild-type p53 protein. Cancer Res. 57: 3562-3568, 1997. PubMed: 9270029 Roesler WJ , et al. The alpha-isoform of the CCAAT/enhancer-binding protein is required for mediating cAMP responsiveness of the phosphoenolpyruvate carboxykinase promoter in hepatoma cells. J. Biol. Chem. 271: 8068-8074, 1996. PubMed: 8626491 Kohler PO , Bridson WE . Isolation of hormone-producing clonal lines of human choriocarcinoma. J. Clin. Endocrinol. 32: 683-687, 1971. |
