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FITC標(biāo)記的禽腦脊髓炎病毒AEV抗體

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產(chǎn)品簡介

FITC標(biāo)記的禽腦脊髓炎病毒AEV抗體產(chǎn)品介紹：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

詳細(xì)介紹

英文名稱Anti-AEV polyprotein/FITC
中文名稱FITC標(biāo)記的禽腦脊髓炎病毒AEV抗體
別    名Avian encephalomyelitis virus; Genome polyprotein; RNA-directed RNA polymerase 3D-PO; P3D-POL; POLG_AEVCA; AEVgp1 aev polyprotein [ Avian encephalomyelitis virus ].
說 明 書100ul  
研究領(lǐng)域細(xì)胞生物  免疫學(xué)  細(xì)菌及病毒  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Avian Encephalomyelitis virus
產(chǎn)品應(yīng)用IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
性    狀Lyophilized or Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from AEV polyprotein, RNA-directed RNA polymerase 3D-POL
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹Function:
Capsid proteins VP1, VP2, and VP3 form a closed capsid enclosing the viral positive strand RNA genome. All these proteins contain a beta-sheet structure called beta-barrel jelly roll. Together they form an icosahedral capsid (T=3) composed of 60 copies of each VP1, VP2, and VP3, with a diameter of approximay 300 Angstroms. VP1 is situated at the 12 fivefold axes, whereas VP2 and VP3 are located at the quasi-sixfold axes (By similarity). 
VP0 precursor is a component of immature procapsids. The N-terminal domain of VP0, protein VP4, is needed for the assembly of 12 pentamers into the icosahedral structure. Unlike other picornaviruses, AEV VP4 may not be myristoylated (By similarity). 
Protein 2B and 2BC precursor affect membrane integrity and cause an increase in membrane permeability (By similarity). 
Protein 2C associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity). 
Protein 3A, via its hydrophobic domain, serves as membrane anchor (By similarity). 
Protein 3B is covalently linked to the 5'-end of both the positive-strand and negative-strand genomic RNAs. It acts as a genome-linked replication primer (By similarity). 
Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity). 
RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).


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