| 英文名稱 | Anti-AGFG1/FITC |
| 中文名稱 | FITC標記的艾滋病病毒復制結合蛋白抗體 |
| 別 名 | HIV 1 Rev binding protein; RAB; Rev/Rex activation domain-binding protein; RIP; AGFG1; AGFG1_HUMAN; Arf-GAP domain and FG repeats-containing protein 1; ArfGAP with FG repeats 1; HIV-1 Rev-binding protein; HRB; Nucleoporin like protein RIP; Nucleoporin-like protein RIP; Rev interacting protein; Rev-interacting protein. |
| 說 明 書 | 100ul |
| 研究領域 | 細胞生物 免疫學 信號轉導 細菌及病毒 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Human, Mouse, Rat, Horse, |
| 產品應用 | IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 58kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human AGFG1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產品介紹 | background:
Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.
Function:
Required for vesicle docking or fusion during acrosomebiogenesis (By similarity). May play a role in RNA trafficking orlocalization. In case of infection by HIV-1, acts as a cofactor forviral Rev and promotes movement of Rev-responsiveelement-containing RNAs from the nuclear periphery to thecytoplasm. This step is essential for HIV-1 replication.
Subunit:
Interacts with EPS15R and EPS15. Interacts with FCHO1.
Subcellular Location:
Nucleus. Cytoplasmic vesicle.
Tissue Specificity:
Ubiquitously expressed.
Post-translational modifications:
O-glycosylated (By similarity).
Similarity:
Contains 1 Arf-GAP domain. |
