抗酒石酸酸性磷酸酶（TRAP，tartrate-resistant acid phosphatase）為破骨細胞的標志酶，特異地分布于破骨細胞中，為破骨細胞所*。通常作為鑒別破骨細胞的重要標志物，使破骨細胞呈紅色。Kamiya艾美捷抗酒石酸酸性磷酸酶TRAP染色試劑盒，經眾多Nature文章使用認證！

Kamiya艾美捷抗酒石酸酸性磷酸酶TRAP染色試劑盒應用：

① 破骨細胞TRAP染色

② 破骨細胞培養上清液中TRAP活性的測定

Kamiya艾美捷抗酒石酸酸性磷酸酶TRAP染色試劑盒Nature文章結果鑒賞：

①【Nature Medicine, IF=87.2】  

TRAP stain: TRAP染色 (osteoclasts (o/c))

圖1

② 【Nature Biomedical Engineering, IF=29.2】A multi-organ chip with matured tissue niches linked by vascular flow  

TRAP Activity: TRAP活性

圖2

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Kim, Jinkoo, et al. "Erythropoietin mediated bone formation is regulated by mTOR signaling."Journal of cellular biochemistry113.(2012): 220-228.

Lee, Yu-Chen, et al. "Src family kinase/abl inhibitor dasatinib suppresses proliferation and enhances differentiation of osteoblasts."Oncogene 29.22 (2010): 3196-3207.

Lu, Yi et al. "Activation of MCP-1/CCR2 axis promotes prostate cancer growth in bone". Clinical & experimental metastasis vol.26,2 (2009): 161-9. doi:10.1007/s10585-008-9226-7