背景資料

Cyclosporin A is an immunosuppressant drug that binds cyclophilin D, inhibiting the phosphatase activity of calcineurin in T cells (IC50 = 5 nM).{24989,20555,25125} It blocks the transcription of genes involved in T cell activation by interfering with the calcineurin-driven nuclear import of the transcription factor NFAT.{24989,21639,21213} Because of its powerful immunosuppressant activity, cyclosporin A has long been used for the prevention of transplant rejection.{25124}

產品描述

An immunosuppressant drug that binds cyclophilin D, inhibiting the phosphatase activity of calcineurin in T cells (IC50 = 5 nM), which interferes with the nuclear import of NFAT, a transcription factor involved in T cell activation; used for the prevention of transplant rejection

保存建議

建議您在收到開曼生物品牌的Cyclosporin A (25 mg)產品后置于-20度保存，產品有效期為730天.

其他

開曼生物向全球科學工作者提供多研究領域的生化、免疫試劑和分析試劑盒，其產品被廣泛應用于腫瘤、氧化氮、神經學、凋亡、氧化性損傷、內分泌學等不同研究領域.開曼生物可提供用于檢測的特色試劑盒，如：類花生酸類物質、游離的生物標志、環核苷、激素及氧化氮等；也提供多種高質量試劑，包括：類花生酸類物質、氧化氮試劑及許多相關脂質、脂肪酸、酶和抗體.作為開曼生物在中國的區域總代理，艾美捷科技有限公司將為中國客戶提供的開曼生物產品以及客戶訂制化服務.