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上海研晶生化試劑有限公司
閱讀：255發(fā)布時(shí)間：2011-10-13
記者從日前在京召開(kāi)的2011年針灸研討會(huì)上獲悉，首都醫(yī)科大學(xué)附屬北京中醫(yī)醫(yī)院針灸中心經(jīng)臨床研究證實(shí)，傳統(tǒng)的中醫(yī)針*法可有效預(yù)防偏頭痛的復(fù)發(fā)和加重。相關(guān)研究論文近日發(fā)表在醫(yī)學(xué)期刊《疼痛》上，成為中國(guó)大陸首篇發(fā)表于該雜志的臨床研究論文。該文還被醫(yī)學(xué)生物學(xué)機(jī)構(gòu)Faculty of 1000 medicine（千名醫(yī)學(xué)家）收錄。
據(jù)了解，作為臨床常見(jiàn)病之一，偏頭痛發(fā)病率高，且危害嚴(yán)重。目前，我國(guó)18歲~65歲人群的偏頭痛患病率高達(dá)9.3%，且有逐年升高趨勢(shì)。*頭痛在中國(guó)已經(jīng)有數(shù)千年的歷史。北京中醫(yī)醫(yī)院針灸中心自2004年設(shè)立頭痛專家門診，開(kāi)展了基于“金針王樂(lè)亭”、國(guó)醫(yī)大師賀普仁等多位針灸學(xué)家治痛經(jīng)驗(yàn)的頭痛研究。
據(jù)該中心主任王麟鵬介紹，該項(xiàng)目采取單盲、雙模擬、隨機(jī)對(duì)照的形式，在國(guó)內(nèi)5家醫(yī)院的針灸科共招募140名無(wú)先兆偏頭痛患者，隨機(jī)分為兩組，分別為治療組（針灸加安慰劑）和對(duì)照組（假針加氟*）。兩組患者每周*3次，每晚口服藥物。結(jié)果顯示，4周后，治療組偏頭痛的有效緩解率為59%，對(duì)照組為40%；治療組疼痛天數(shù)平均下降4.1天，對(duì)照組平均下降1.9天。16周后，治療組有效緩解率為56%，對(duì)照組為37%；治療組疼痛天數(shù)平均下降4.1天，對(duì)照組平均下降2天。
研究人員據(jù)此認(rèn)為，針灸可以作為偏頭痛的預(yù)防復(fù)發(fā)和加重的方法，其治療效果也優(yōu)于此前國(guó)外的相關(guān)研究。由于其研究方法的新穎和重要性，該論文還被醫(yī)學(xué)生物學(xué)機(jī)構(gòu)“千名科學(xué)家”收錄。（生物谷 Bioon.com）
doi:10.1016/j.pain.2011.04.006
PMC:
PMID:
Efficacy of acupuncture for migraine prophylaxis: A single-blinded, double-dummy, randomized controlled trial
Lin-Peng Wang,Xiao-Zhe Zhang,Jia Guo,Hui-Lin Liu,Yan Zhang,Cun-Zhi Liu,Jing-Hong Yi,Li-Ping Wang,Ji-Ping Zhao,Shan-Shan Li
Summary This multicenter, double-dummy trial suggested that acupuncture was more effective than flunarizine in decreasing days of migraine attacks. Abstract Insufficient clinical trial data were available to prove the efficacy of acupuncture for migraine prophylaxis. A multicenter, double-dummy, single-blinded, randomized controlled clinical trial was conducted at the outpatient departments of acupuncture at 5 hospitals in China to evaluate the effectiveness of acupuncture. A total of 140 patients with migraine without aura were recruited and assigned randomly to 2 different groups: the acupuncture group treated with verum acupuncture plus placebo and the control group treated with sham acupuncture plus flunarizine. Treated by acupuncture 3 times per week and drugs every night, patients from both groups were evaluated at week 0 （baseline）, week 4, and week 16. The primary outcome was measured by the proportion of responders （defined as the proportion of patients with a reduction of migraine days by at least 50%）. The secondary outcome measures included the number of migraine days, visual analogue scale （VAS, 0 to 10cm） for pain, as well as the physical and mental component summary scores of the 36-item short-form health survey （SF-36）. The patients in the acupuncture group had better responder rates and fewer migraine days compared with the control group （P<.05）, whereas there were no significant differences between the 2 groups in VAS scores and SF-36 physical and mental component summary scores （P>.05）. The results suggested that acupuncture was more effective than flunarizine in decreasing days of migraine attacks, whereas no significantly differences were found between acupuncture and flunarizine in reduction of pain intensity and improvement of the quality of life.
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