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閱讀:305發布時間:2014-5-8
胰島素樣生長因子I受體抗體,Anti-IGF1R抗體Background: This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1. PubMed:12138094 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of IGF1R and INSR isoform Short are activated by IGF1, IGF2 and insulin. In contrast, PubMed:16831875 shows that hybrid receptors composed of IGF1R and INSR isoform Long and hybrid receptors composed of IGF1R and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinity for insulin
胰島素樣生長因子I受體抗體,Anti-IGF1R抗體別 名 CD221; CD221 antigen; IGF1 Receptor; IGF 1 receptor; IGF 1R; IGF I receptor; IGF1R; IGFIR; IGFIRC; Insulin like growth factor 1 receptor; Insulin like growth factor 1 receptor precursor; JTK13; MGC142170; MGC142172; IGF1R_HUMAN; Insulin-like growth factor 1 receptor beta chain; IGF 1 receptor; IGF-1R; IGF I receptor; IGF-I receptor
:021 60340850 021 60340830 021 60340820
客服 :372584443 1091953152 827774711
胰島素樣生長因子I受體抗體,Anti-IGF1R抗體相關產品:
Anti-EAG1(Ether-a-go-go potassium channel 1) 鉀離子通道蛋白EAG1抗體
Anti-HERG/KCNH2/ERG 特異性鉀離子通道蛋白抗體
Anti-HA tag HA tag標簽抗體
Anti-HA tag HA tag標簽抗體
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Anti-HBeAg(Mouse human Anti-HbeAg Monoclonal Antibody)(2) 小鼠抗人乙肝e抗原抗體(2)
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