【中文名稱】：磷酸化腫瘤抑制基因P53抗體/P53（Ser392）抗體報(bào)價(jià)  

【產(chǎn)品貨號(hào)】：BYK-1650R

【產(chǎn)品規(guī)格】：0.1ml/0.2ml
【產(chǎn)品價(jià)格】：詢價(jià)（電詢 客服:）
【抗體來源】：Rabbit OR Mouse
【貨 期】： 現(xiàn)貨
【性 狀】： Lyophilized or Liquid
【濃 度】： 1mg/1ml
【亞 型】： IgG
【貯 存】： 貯存于-20℃.
【產(chǎn)品用途】：科研實(shí)驗(yàn)，用于免疫組化實(shí)驗(yàn)，WB實(shí)驗(yàn)，相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體，F(xiàn)ITC標(biāo)記，BIO等。

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磷酸化腫瘤抑制基因P53抗體/P53（Ser392）抗體報(bào)價(jià) 產(chǎn)品說明：
p53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. p53 can apparently be phosphorylated by ATM, ATR, and DNAPK at Ser15; the phosphorylation impairs the ability of MDM2 to bind p53, promoting both the accumulation and functional activation of p53 in response to DNA damage. Chk2 and Chk1 can phosphorylate p53 at Ser20, enhancing its tetramerization, stability and activity. p53 is phosphorylated at Ser392 in vivo and by CAK in vitro. Phosphorylation of p53 at Ser392 is altered in human tumors and has been reported to influence the growth suppressor function, DNA binding and transcriptional activation of p53. p53 is phosphorylated at Ser6 and Ser9 by ck1d and ck1e both in vitro and in vivo. Phosphorylation of p53 at Ser46 is important in regulating the ability of p53 to induce apoptosis. In vivo phosphorylation of p53 at Ser33 by cdk7/cyclin H and in response to UV irradiation has been observed.

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Anti-PAX3（Paired box gene 3）  配對(duì)盒基因3抗體
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