囊泡谷氨酸轉運體（VGLUTs）包括3個成員，VGLUT1、VGLUT2和VGLUT3。囊泡谷氨酸轉運體（VGLUTs）的異常會導致興奮性神經遞質谷氨酸的異常，從而誘發多種神經系統疾病。

囊泡型谷氨酸轉運蛋白1VGLUT1，又稱BNPI和SLc17a7，zui初被鑒定為腦特異性磷酸轉運蛋白。與相關的VGLUT-2一樣，VGLUT-1對谷氨酸的攝取和儲存既是必要的，也是充分的，因此構成了谷氨酸能表型的決定因素。這兩種VGLUT都不同于血漿膜轉運蛋白，因為它們是由跨囊泡膜的質子電化學梯度驅動的。

VGLUT 1和VGLUT 2呈現互補表達模式?？偠灾?，它們是目前谷氨酸能神經末梢和谷氨酸能突觸的標記物。

VGLUT 1 - 135 302，這個來自德國SySy的囊泡谷氨酸轉運體1（抗體），特異性針對VGLUT1蛋白（經過敲除驗證K.O），作為谷氨酸能神經末梢的標記物。（使用說明：VGLUT 1在煮沸后聚集，因此建議對未煮沸的樣品進行SDS-PAGE分析。）

發表文章超100+：Nature, Cell，課代表~

WB（23+）：

Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels.

Cheret C, Ganzella M, Preobraschenski J, Jahn R, Ahnert-Hilger G

Cell reports (2021) 342: 108623. 135 302 WB, ICC; tested species: human,mouse

IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2α.

Tanabe Y, Naito Y, Vasuta C, Lee AK, Soumounou Y, Linhoff MW, Takahashi H

Nature communications (2017) 81: 408. 135 302 WB

IP（2+）：

Regulation of the Hippocampal Network by VGLUT3-Positive CCK- GABAergic Basket Cells.

Fasano C, Rocchetti J, Pietrajtis K, Zander JF, Manseau F, Sakae DY, Marcus-Sells M, Ramet L, Morel LJ, Carrel D, Dumas S, et al.

Frontiers in cellular neuroscience (2017) 11: 140. 135 302 WB, IP; tested species: mouse

ICC（33+）：

Neuronal defects in a human cellular model of 22q11.2 deletion syndrome.

Khan TA, Revah O, Gordon A, Yoon SJ, Krawisz AK, Goold C, Sun Y, Kim CH, Tian Y, Li MY, Schaepe JM, et al.

Nature medicine (2020) : . 135 302 ICC; tested species: human

Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program.

Karow M, Camp JG, Falk S, Gerber T, Pataskar A, Gac-Santel M, Kageyama J, Brazovskaja A, Garding A, Fan W, Riedemann T, et al.

Nature neuroscience (2018) : . 135 302 ICC; tested species: human

IHC（40+）：

Context-Specific Striatal Astrocyte Molecular Responses Are Phenotypically Exploitable.

Yu X, Nagai J, Marti-Solano M, Soto JS, Coppola G, Babu MM, Khakh BS

Neuron (2020) : . 135 302 IHC; tested species: mouse

Hyperactivity with Disrupted Attention by Activation of an Astrocyte Synaptogenic Cue.

Nagai J, Rajbhandari AK, Gangwani MR, Hachisuka A, Coppola G, Masmanidis SC, Fanselow MS, Khakh BS

Cell (2019) : . 135 302 IHC; tested species: mouse

Other（1+）：

Transplantation of neurons derived from human iPS cells cultured on collagen matrix into guinea-pig cochleae.

Ishikawa M, Ohnishi H, Skerleva D, Sakamoto T, Yamamoto N, Hotta A, Ito J, Nakagawa T

Journal of tissue engineering and regenerative medicine (2017) 116: 1766-1778. 135 302

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文章來源：艾美捷科技