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聯(lián)系我時(shí),請(qǐng)告知來(lái)自 智慧城市網(wǎng)博研生物現(xiàn)貨提供“Anti- Caspase-3抗體,*活化半胱胺酸蛋白酶蛋白3抗體",產(chǎn)品質(zhì)量保證,提供,有任何質(zhì)量問(wèn)題可免費(fèi)包退包換,咨詢!
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【產(chǎn)品名稱】:Anti- Caspase-3抗體,*活化半胱胺酸蛋白酶蛋白3抗體
【產(chǎn)品編號(hào)】:BYK-0081R
【產(chǎn)品規(guī)格】:0.1ml/0.2ml
【產(chǎn)品價(jià)格】:詢價(jià)(電詢或客服)
【抗體來(lái)源】:Rabbit OR Mouse or Goat
【產(chǎn)品用途】:科研實(shí)驗(yàn),用于ELISA實(shí)驗(yàn)、免疫組化實(shí)驗(yàn),WB實(shí)驗(yàn),IF實(shí)驗(yàn)等,可,索取產(chǎn)品說(shuō)明書(shū)!
【性 狀】: Lyophilized or Liquid
【濃 度】: 1mg/1ml
【亞 型】: IgG
【貯 存】: 貯存于-20℃.
【相關(guān)標(biāo)記】:HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
【產(chǎn)品別名】:Caspase-3 subunit p17; APOPAIN; CASP3; Caspase 3 apoptosis related cysteine protease; Caspase3; CPP32; CPP32B; Cysteine protease CPP32; Human cysteine protease CPP32 isoform alpha mRNA complete cds; PARP cleavage protease; SCA 1; SCA1; SREBP cleavage activity 1; Yama; CASP3_HUMAN; Caspase-3; CASP-3; Apopain; Protein Yama; SREBP cleavage activity 1; SCA-1.
【產(chǎn)品介紹】:The caspase family of cysteine proteases play a key role in apoptosis. Caspase 3 is the most extensively studied apoptotic protein among caspase family members. Caspase 3 is synthesized as inactive pro enzyme that is processed in cells undergoing apoptosis by self proteolysis and/or cleavage by other upstream proteases (e.g. Caspases 8, 9 and 10). The processed form of Caspase 3 consists of large (17kDa) and small (12kDa) subunits which associate to form an active enzyme. Caspase 3 is cleaved at Asp28 Ser29 and Asp175 Ser176. The active Caspase 3 proteolytically cleaves and activates other caspases (e.g. Caspases 6, 7 and 9), as well as relevant targets in the cells (e.g. PARP and DFF). Alternative splicing of this gene results in two transcript variants which encode the same protein. In immunohistochemical studies Caspase 3 expression has been shown to be widespread but not present in all cell types (e.g. commonly reported in epithelial cells of skin, renal proximal tubules and collecting ducts). Differences in the level of Caspase 3 have been reported in cells of short lived nature (eg germinal centre B cells) and those that are long lived (eg mantle zone B cells). Caspase 3 is the predominant caspase involved in the cleavage of amyloid beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.
Reacts with Caspase-3 subunit p17 and precursor.
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